Table of Contents

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What's New in Current Protocols in Nucleic Acid Chemistry
Supplement 39, December 2009

Unit 3.18 Nonenzymatic Oligomerization of Activated Nucleotides on Hairpin Templates
         Abstract | Full Text:  HTML   PDF

Unit 4.38 Carbohydrate-Oligonucleotide Conjugates
         Abstract | Full Text:  HTML   PDF

Unit 9.2 Design, Synthesis, and Amplification of DNA Pools for In Vitro Selection
         Abstract | Full Text:  HTML   PDF

Unit 16.3 Chemical Modification of siRNA
         Abstract | Full Text:  HTML   PDF

Welcome to new editorial board members Martin Egli and Yogesh S. Sanghvi!

Goodbye and thank you to retiring editorial board members Serge Beaucage and Don Bergstrom for their invaluable contributions to the launch and development of the series over the past 10 years.

Published in association with International Society for Nucleosides, Nucleotides & Nucleic Acids (IS3NA) , Current Protocols in Nucleic Acid Chemistry is equally valuable for biotech, pharmaceutical, and academic labs. It is the resource for designing and running successful research projects in the rapidly growing and changing field of nucleic acid, nucleotide, and nucleoside research.

Updated every three months in all formats, CPNAC is constantly evolving to keep pace with the very latest discoveries and developments. A year of these quarterly updates is included in the initial CPNAC purchase price. That's 500 pages of new (66%) and revised (34%) content on average every year since the initial publication of the work in February 2000! Presently three volumes in its looseleaf print version, CPNAC...

• draws from a unique set of chemistries to synthesize modified nucleic acids, which can be used in structure-function studies, as therapeutic agents, and as tools for molecular biology.
• covers basic to advanced techniques for the synthesis, modification, purification, analysis, and utilization of nucleic acids, nucleotides, and nucleosides.

Edited by: Martin Egli (Vanderbilt Univesity); Piet Herdewijn (Rega Institute of Medical Research); Akira Matsuda (Hokkaido University); Yogesh S. Sangvhi (Rasayan, Inc.); Past Editors: Serge L. Beaucage; Donald E. Bergstrom; Gary D. Glick; Roger A. Jones

Developmental Editor: Marianne Huntley

See is3na.org for information about the society and the 2010 International Roundtable (IRT) meeting.

While the authors, editors, and publisher believe that the specification and usage of reagents, equipment, and devices, as set forth in this book, are in accord with current recommendations and practice at the time of publication, they accept no legal responsibility for any errors or omissions, and make no warranty, express or implied, with respect to material contained herein. In view of ongoing research, equipment modifications, changes in governmental regulations, and the constant flow of information relating to the use of experimental reagents, equipment, and devices, the reader is urged to review and evaluate the information provided in the package insert or instructions for each chemical, piece of equipment, reagent, or device for, among other things, any changes in the instructions or indication of usage and for added warnings and precautions. This is particularly important in regard to new or infrequently employed chemicals or experimental reagents. Moreover, the information presented herein is not a substitute for professional judgment, especially as concerns any applications in a clinical setting or the interpretation of results thereby obtained.